Are Oncology Clinical Studies Facing Challenges?

Published on: 31 August 2017 Last Updated on: 16 August 2019

Oncology clinical trials are a huge growth area and there is understandably a great deal of interest in treatments for cancer.

New treatment strategies such as immunotherapy and personalized medicine mean that clinical oncology has moved into an exciting stage. Demand for clinical studies is growing all the time, and clinical development is moving apace.

Interestingly, these developments mean that great progress is being made, but there have been some problems along the way. In August this year, reports emerged that the sheer number of oncology clinical trials means that pharmaceutical companies are having trouble finding enough patients to test new treatments on.

The issue has arisen due to the appetite for getting new cancer treatments to market, and the fact that these revolutionary treatment strategies are only effective in select patients. Drug companies want to get proprietary drugs to market so they can profit from their research, but testing them requires lots of patients.

Consider the fact that there are now more than 1,000 clinical studies of immunotherapy underway and it’s not hard to see why patient supply has become a problem. Fortunately, there are companies who can help researchers find the patients that they need.

One such company is INC Research, which boasts a team of experienced oncology specialists such as project managers, medical directors, CRAs and executive leadership. Over the past five years, INC Research has managed 310 studies at 7,278 sites involving 34,106 patients. If anyone can help researchers find the right patients, it’s an experienced company like INC Research.

Drug companies that have worked with INC Research report that there are real benefits, such as time- and cost-savings and real-time data gathering. The team has worked on incredibly complex trials involving investigational therapies like monoclonal antibodies, so they are ready for anything that you can throw at them.

Choosing the right clinical research organization (CRO) can make or break a study. INC Research offers a full spectrum service which handles data management and operational strategy, and the team also has a deep knowledge of the regulations related to Early Phase Oncology.

INC Research offers regulatory intelligence services to biotech companies across the globe, making sure that new treatments will get approved and make it to market. After all, improving available treatment options is the reason why companies choose to invest in cancer clinical trials.

From planning a trial to sourcing patients and collecting data, INC Research is a leader in its field. In an incredibly competitive environment, it is important to work with the best. With a long list of happy clients and glowing testimonials, drug companies can rest assured that their cancer clinical trial is in good hands with INC Research.

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How to sleep better when you have cancer

Did you know that a poor sleeping schedule could increase your risk of cancer? It may be responsible for raising the risk of heart conditions, diabetes, and other major illnesses, as well as impair your immunity system. Experts have realized the importance of sleep in addressing these risks. They suggest that people should focus on improving the quality of their sleep to improve their lives. There are a large number of people who are already suffering from these conditions who may have trouble sleeping as a result. Do you have cancer? This guide can help you sleep better at night. How does cancer interfere with sleep? Cancer and cancer treatment can induce sleep problems even in people without a previous history of troubled sleep. You may be faced with excessive fatigue throughout the day from both your condition and treatment, which will impact your ability to get a full night's rest. Both could increase your risk of developing a sleep condition significantly. Sleep better for your better health habits during times of cancer. Cancer may cause both physical and emotional distress, which will affect your sleep. These can be very disruptive to your sleep patterns. The medication and treatment plans on offer for people with this condition will also cause sleep problems. Chemotherapy and radiation treatment will often carry side effects such as pain, night sweatband nausea, which will make it difficult to sleep at night. There are many secondary conditions that may cause other sleep complications that could arise from treatment. You may also face trouble sleeping from anemia and hypothyroidism. The most common sleep disorder among cancer patients is hypersomnia, which increases the urge to sleep throughout the day. Some symptoms of hypersomnia include having trouble staying awake, sleeping for more than 9 hours at a time and experiencing persistent sleepiness despite actually getting recommended amounts of sleep. It is linked with certain types of cancer, but may also be a result of treatment. About one-third of cancer patients experience the reverse condition, insomnia. Some of the symptoms of this include difficulty falling and staying asleep, feeling unrefreshed after a full period of sleep and regular early mornings. Most insomnia in cancer patients arises from chronic pain, but may also result from treatment. Cancer also increases the risk of disruptive sleep apnea and sleep-disordered breathing problems. It may be symptomized by poor concentration and memory levels, headaches, excessive sleepiness, chronic snoring, dry mouth, and sore throat, and decreased libido. How to sleep better when you have cancer Cancer can cause chronic pain, which will affect your sleep. You may also have a poor sleep schedule because of the treatment options which can take a toll on your body and mind. It is important that you maintain a healthy sleep routine to maximize your ability to get recommended amounts of rest every night. These are a few tips to help you sleep better when you are living with cancer. Restore balance to your sleep/wake rhythm You will be less likely to sleep if your circadian rhythm is compromised. Since it is affected by exposure to light, you can control your sleep/wake cycle by regulating your exposure to light. During the day, you should take in as much natural light as possible. At night, you should limit the amount of light to improve your ability to fall asleep. If you are facing increased fatigue from your treatment, you could consider healthy and energetic food options, as well as exercise, to build up your energy levels. This will help you stay up during the day and restore your natural rhythm for a better night. Maintain a sleep schedule You should limit your sleep to about the same length every night for consistency. Even on the weekends, you should only allow yourself at most one more hour in bed. This will help your brain build a positive association with your sleep environment, which will enable you to sleep and wake up within your schedule. You will be better able to get a good night's rest if you have an orderly schedule to help you out. Try out essential oils Essential oils are great for addressing chronic pain and managing other effects of cancer. You should incorporate these oils into your lifestyle because they can alleviate some of the effects of both your condition and treatment. Essential oils such as lavender can be applied topically as a form of aromatherapy to induce sleep. Other oils such as peppermint and tea tree oil offer anti-inflammatory effects. The pain reduction and effect on snoring will help you sleep without any disruptions. Limit blue light Blue light exposure can confuse your brain into tanking that it is still day time. It is emitted by phones, computers and other devices with a screen. It could affect your ability to fall asleep. You should make sure to have all these devices off at least 90minutes before bed to help you sleep better. Create a good sleeping environment Cancer patients need an uninterrupted night. However, this can be difficult because of the pain and other effects of treatment. You can improve your ability to get a full night’s rest by improving the level of comfort in your sleep environment. You could consider getting new mattresses, sheets and pillows to elevate your level of comfort. Visit bear mattress for a great selection of comfortable options. Aside from having comfortable sheets, warm pillows and a great mattress, you may also need to limit your exposure t light and noise to help you get to sleep. Some music could help you sleep better, but care must be taken to ensure it is not disruptive and accompanies your night. You could also consider natural and patterned sounds to help you fall asleep. Final word Sleep is restorative and beneficial for your health. It has been linked with an increased likelihood of successful cancer treatment; with people who sleep better likely to go into remission. Having as little as 6 hours or as much as 10 hours of sleep in a 24-hour period could negatively affect your ability to beat cancer. You need to develop and commit to a great sleeping schedule to increase you odds of survival. Sleep quality and hygiene could be just as integral to your survival as a good diet and treatment plan. Read Also: Can Breast Augmentation Cause Cancer? The Advantages And Disadvantages Of Non-Alcoholic Spirits

Vaping in the Workplace: Legal Considerations

Vapes have been around for over a decade now, being supplied by various companies such as VIP. There has been much debate of late about vaping, and where it should be allowed. Currently, many workplaces and businesses treat vaping the same as smoking and thus do not allow it indoors at all. Given that vaping is said to be far less harmful than tobacco smoke, it is seen as an effective way of helping smokers to quit, and almost as a medical tool for doing so. As such, there have been developments in the political sphere regarding vaping indoors, so here are some of the legal considerations around vaping in the workplace. Government Policy The government has recently issued a set of guidelines for employers and organizations regarding vaping in the workplace. In these, they state that vaping should be treated completely differently to smoking, given that it is far less dangerous and could even be beneficial to those trying to quit. They acknowledge that different workplaces will have different policies in place given that there are different operational risks (between a factory and a school, for example) and that each workplace should put an informed policy in place which is based on the risks posed to the likes of bystanders, staff, and children. Which Considerations Must Govern Policy? As such, it is currently legal to smoke in the workplace, so long as the employer allows it in their policy. The onus is now on employers, rather than the law, to decide whether it is safe to vape, but this means that each employer should still make essential considerations before allowing it. They must, for instance, consider the safety of each employee, and ensure that any smoke emitted from a vape does not hamper this. In a place that requires excellent visibility at all times (a plane cockpit, for instance), allowing vaping would most likely be a bad idea, whereas in a wide-open space like a factory vaping would most likely be harmless. Customers/Clients Whilst it may not be a legal consideration as such, companies and organizations should also think about the effect vaping may have on the customers/clients which they deal with on a daily basis, and whether vaping may be harmful to their health or overall experience of the business organization. It is likely that, if employers allow vaping, it will be in areas in which customers do not go, or in which vape smoke will have minimal impact on their experience. In the highly unlikely event of a customer having an asthma attack, because of vape smoke (for example), it is possible that legal action could be taken against the employer, which would not only damage their profits but also their reputation. So, although employers should carefully consider the use of vapes in the workplace, attitudes towards vapes themselves are changing, and it is likely that they will be much more widely accepted in the years to come. With laws having been relaxed, it could well be the case that the majority of workplaces will allow vaping in the near future. Read Also : Benefits Of E-Cigarettes Over Traditional Smoking How Does Smoking Weed Affect The Society

Causes of Male & Female Infertility

Infertility is very common than we think and. Close to 50 percent of couples all over the world experience infertility at one point in their lifetime. Infertility has become much more common in 2nd pregnancy than in the 1st one. The main reason for this is age. As men and women age, their fertility health tends to deteriorate. Hence it is very important to understand one’s fertility health and fertility facts while you plan and postpone your parenthood goals. You don’t want to make a decision that may affect you negatively in the future. Get Fertility Test Before Marriage: Most of us are not aware of the fertility factor nor how it is affecting us. You may blame your partner for being infertile yet the problem is with you. One way to evaluate this is to get a fertility test done. But how many of us are so comfortable getting a fertility test done before marriage. This is something we should start thinking about. Don’t wait until you are unable to get a baby during marriage before you can decide to go for a fertility test. Understand your reproductive health from the onset so that you can start preparing in good time. The Fertility Factor and Age: The fertility factor varies from person to person. So there is no one size fits for. If someone is telling you that all men will be fertile until the age of 40, please do not believe that. I have seen men who are as old as 80 years making women pregnant. Your biological clock is different from the other person's. It also depends on how well you have taken care of your health. Take good care of your health if you want to be fertile for long. During my visit to one of the IVF centers in Mumbai, I learned that the average age of people affected by infertility is between 27 – 35 and hence it is not only a factor of age. While studying this phenomenon deeper, I found that there are multiple things involved. Let me discuss some of these factors below even though I have already mentioned some of the above. Factors That Influence Fertility: Habits and lifestyle are the core issues that affect the fertility of any human being. Sleeping habits, how we eat, and to a certain extent how we live. Make sure you get enough sleep at night so as not to affect the normal functionality of your body system. Straining the body too much can even affect the functionality of the reproductive system. Get enough rest and exercise your body from time to time so as to keep fit. Most of us here are affected by the westernized phenomenon of eating fast foods or processed foods. These foods contain chemicals that can kick our fertility out. Drinking and smoking are on a rise. Peer pressure and society are to blame. Avoid eating junk food and instead, stick to a healthy diet. Movies show such behaviors to be cool and our generation grasp it very keenly. This kind of lifestyle is leading to an increase in obese cases and thyroid patients are on a high. Women are more prone to PCOD/PCOS, fibroids, ovarian cysts, and endometriosis due to such an unhealthy lifestyle. Female infertility treatment is something that has become one of the most searched terms on the internet. Summary: Concluding the topic, it is very important to understand that our body is made to withstand only a certain level of exposure to toxins and after that, it starts losing its nature. Hence please do understand this and get yourself a fertility quotient test done when you feel it is essential for you to know yourself better and plan things ahead. Read Also : Golden Pregnancy Care Tips For All Expectant Women 9 Tips For Staying Fit And Healthy During Pregnancy Yoga For Pregnant Women

Are Oncology Clinical Studies Facing Challenges?

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How to sleep better when you have cancer

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Are Oncology Clinical Studies Facing Challenges?

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How Can A Cardiologist Save Your Life?

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Content Rally wrapped around an online publication where you can publish your own intellectuals. It is a publishing platform designed to make great stories by content creators. This is your era, your place to be online. So come forward share your views, thoughts and ideas via Content Rally.

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