Are Oncology Clinical Studies Facing Challenges?

Published on: 31 August 2017 Last Updated on: 16 August 2019

Oncology clinical trials are a huge growth area and there is understandably a great deal of interest in treatments for cancer.

New treatment strategies such as immunotherapy and personalized medicine mean that clinical oncology has moved into an exciting stage. Demand for clinical studies is growing all the time, and clinical development is moving apace.

Interestingly, these developments mean that great progress is being made, but there have been some problems along the way. In August this year, reports emerged that the sheer number of oncology clinical trials means that pharmaceutical companies are having trouble finding enough patients to test new treatments on.

The issue has arisen due to the appetite for getting new cancer treatments to market, and the fact that these revolutionary treatment strategies are only effective in select patients. Drug companies want to get proprietary drugs to market so they can profit from their research, but testing them requires lots of patients.

Consider the fact that there are now more than 1,000 clinical studies of immunotherapy underway and it’s not hard to see why patient supply has become a problem. Fortunately, there are companies who can help researchers find the patients that they need.

One such company is INC Research, which boasts a team of experienced oncology specialists such as project managers, medical directors, CRAs and executive leadership. Over the past five years, INC Research has managed 310 studies at 7,278 sites involving 34,106 patients. If anyone can help researchers find the right patients, it’s an experienced company like INC Research.

Drug companies that have worked with INC Research report that there are real benefits, such as time- and cost-savings and real-time data gathering. The team has worked on incredibly complex trials involving investigational therapies like monoclonal antibodies, so they are ready for anything that you can throw at them.

Choosing the right clinical research organization (CRO) can make or break a study. INC Research offers a full spectrum service which handles data management and operational strategy, and the team also has a deep knowledge of the regulations related to Early Phase Oncology.

INC Research offers regulatory intelligence services to biotech companies across the globe, making sure that new treatments will get approved and make it to market. After all, improving available treatment options is the reason why companies choose to invest in cancer clinical trials.

From planning a trial to sourcing patients and collecting data, INC Research is a leader in its field. In an incredibly competitive environment, it is important to work with the best. With a long list of happy clients and glowing testimonials, drug companies can rest assured that their cancer clinical trial is in good hands with INC Research.

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How to Help Someone Overcome Addiction in Illinois

It’s never easy watching someone you care about go through something like addiction. Many times, people in this situation watch the person they care about to deteriorate and become a different person. If you think your loved one is addicted but you’re not sure, be on the lookout for these warning signs. Their behavior has changed. You notice them becoming more withdrawn, angry, combative, or abusive towards you. You notice them becoming obsessive They’re hiding things from you. Maybe you found needles or empty vodka bottles under their bed or in their bathroom They’ve come home bruised or beaten up but won’t tell you what happened They aren’t sleep They slur their words They’re losing weight or their outward appearance has changed for the worse. If your loved one shows any of these signs, there’s a good chance they might be addicted. If you’re watching someone you love spiral into addiction, there are ways you can help to overcome addiction. Here’s how. 6 Ways To Someone You Know Overcome Addiction In Illinois 1. Call your local rehab center Places like Lincoln Recovery or your local hospital are a great resource for you to tap into. They’ll be able to help you determine the best treatment options for your loved one without making you or them feel ashamed. They’ll be able to give you advice and tools. They can also help you plan something called an intervention. An intervention is when family and friends of the addict’s life come together to make their loved one understand that they need help. Interventions must be planned so they don’t cause more problems. While it’s going to be awkward and uncomfortable, an intervention that’s done right can gently push your loved one on the path to recovery. 2. Establish trust This is a huge thing. Often trust is broken between addicts and the people they love the most, and while it may be difficult to achieve, getting them to trust you is so important. Otherwise and intervention won’t work properly. To start building trust with an addict, you have to learn not to nag, yell, exaggerate, lecture, or engage in any substances they’re addicted to. Asking them to stop drinking when they see you drinking, even if it’s only a small glass of wine at night, can make them defensive. Trust will also help prevent stress. If they trust you more, they’ll be less stressed and feel more comfortable opening up to you about their addiction. Most addicts know they have a problem deep down, they just don’t want to admit it out loud and make it real. Don’t do anything that will keep them from opening up to you about it. Watch their body language to help you determine if your attempts at trust-building are working. If you notice them growing stiff or becoming agitated pull back and try again another time. 3. Never blame Even if the person who’s addicted made you lose money, your reputation, etc. do not try to blame them for it. While they need to take responsibility for their behavior, blaming them for things while they’re addicted will get you nowhere. It will only make them more resistant to change, defensive, and closed off. Speak in the first person, only about how you feel or what you think. Whenever you talk to them about their addiction, use “I” statements. “You” statements can come across as blameful and can do the opposite of what you hope to achieve in the conversation. Avoid insults and negativity at all costs because that is the blameful language that will make them defensive. For more information on using “I” statements, click here. 4. Always practice empathy You see how dangerous it is to blame the addict in any way, either for their addiction or their behavior. Leading with empathy, whether your staging an intervention or not, can help the addict feel more comfortable and open up. Tell them that you understand they’re hurting, and while you don’t know what they’re going through firsthand, you’re there to help in any way you can. You want to be a part of the solution. Offer assistance in any way you can. By doing this, you might find that the person has been waiting for someone to talk to them about it but has been too afraid to bring it up themselves. 5. Prepare for backlash What you have to understand is that addiction affects the chemical balance of the brain. This can make them delusional, combative, or standoffish. They may outright refuse to admit they’re addicted to anything and if they do, they might turn the blame on you. Addicts try to get out of responsibility, and taking responsibility for their addiction is another thing they’re going to try to dance around. Prepare for harsh words, yelling, and threats. Stay calm and listen to everything they have to say. Don’t engage in yelling or screaming or try to push the blame back on them. It will only make the situation worse. If you feel like you’re in danger, remove yourself from the situation or call the police. 6. Stop enabling If you’re allowing the person you love to do drugs in your house or get drunk in your house, stop. Tell them that they aren’t allowed to do that in your home anymore and if they refuse, ask them to leave. It sounds harsh, but they have to learn that there are consequences to their actions. Stop buying them their substance of choice. Practice sobriety yourself so you don’t have alcohol or drugs lying around the house for them to consume. If they frequently borrow your car, remove car privileges so they can’t drive under the influence. Refuse to give them cash. If they say they need a few bucks for food, buy them actual food or not at all. But never give them cash or cards that they can use to purchase drugs or alcohol. While this might seem like you’re not leading with empathy, you are. You don’t have to be mean about doing any of these things. You can simply say, “I don’t want you driving my car under the influence, it’s not safe.” Or “I can’t give you cash, but I can buy you food, water, groceries,” if that’s what you want to do. Just avoid putting the blame or accusing them of anything. To learn the difference between helping and enabling, follow the link. https://www.verywellmind.com/how-to-stop-enabling-an-alcoholic-63083 Read Also: Four Effective Things To Recover From Heroin & Drug Addiction Treatment Spot It Early: 9 Common Signs of Addiction You Need to Look out For Friendships Up in Smoke? 6 Ways Addiction Affects Relationships How To Know If You Have An Addiction: 7 Common Signs

Yoga For Pregnant Women

You’re expecting? Congratulations! Well, it is the most welcoming yet challenging period in a woman’s life. Practice prenatal yoga to deal with changing body and mood swings. Pregnancy is the most pleasing time in a woman’s life. For years, a woman dreams about this day to embrace the pleasure of being a mother. When finally the day arrives, it brings along a lot of challenges, especially for the first time mothers to be. During this period, woman battles with morning sickness, mood swings at varying levels, deal with cramps, fatigue and much more. Due to the various body and emotional changes a woman undergoes during the gestation period, many perceive it as a complication. If you are going through the same and looking for ways to relax, de-stress and stay fit during this life-changing journey, then consider practicing prenatal yoga. The practice of yoga asanas and breathing techniques provides relief from backache, eases morning sickness and much more, ensuring a better gestation period and hassle-free delivery. The aim of yoga is to lessen the labor pains, help the mother bring the unborn child into the world with minimal complications and, to ensure the wellbeing of the mother and the baby both. In addition to this, it provides numerous physical and mental benefits to the mother, like increasing the endurance and strength of muscles required for natural childbirth, improving the balance as body undergoes rapid changes, helping you to focus on your breathing that can be applied during labor pain, developing maternal bond with the child and so many wonderful benefits. A pregnant woman undergoes several body changes. Yoga can be the ideal way to keep the mom-to-be in shape. Those beginners who do not follow a regular yoga regime are advised not to rush into the practice without medical consent. Keeping in mind all the precautions and health considerations, here is a list of yoga asanas for the mothers-to-be: 1. Butterfly or baddha konasana: Sit straight on the floor and stretch your legs fully. Bend your knees and try to bring your feet as close as possible. Join them in namaste position. Keep the hands-on thighs and knees. Take deep breaths. Upon exhalation, press the thighs and knees towards the floor by pressing the elbows over the knees. Hold the pose for as long as you are comfortable. Strengthen pelvis and inner thighs. 2. Mountain Pose or Tadasana: Stand with feet hip distance apart. Keep your spine upright and arms resting by either side. Now, stretch your arms overhead to join them in Namaskar Mudra. Tilt your head backward and fix your gaze at the fingertips. Keep breathing in and out. Hold the pose for few seconds. Strengthens spine and relieves back pain. 3. Cat Pose or Marjariasana: Come onto your fours with knees under your hips and hands under the shoulders. Take a deep breath, lift your chin up and slightly push back your head. Hold the pose for 30 seconds. Exhale and bring your chin close to your chest. Relax your hips and hold the pose for 10 seconds. Slowly release the pose. It improves blood circulation level in the body. Triangle Pose or Trikonasana: Stand with a straight back on the yoga mat. Spread your feet wide about 3-4 feet. Make sure the toes of both the feet are parallel to each other and heels are aligned. Lift your hands up with palms facing downwards. Align them with your shoulders. Bend towards your left side. At the same time, lift your right hand up towards the sky. Turn your head to the left and fix your gaze on the fingertips of the right hand. Hold the pose for 10-20 seconds. The pose improves hip flexibility and eases pregnancy-related digestive issues. Child Pose or Balasana: Kneel on your fours. Keep your knees wide apart about 3-4 feet. Rest your hips on your heels. On an exhalation, bend forward draping your torso between your thighs. Tuck your chin close to your chest and forehead on the ground. Keep your arms extended. Remain in the pose for 5-6 slow breaths. It provides relief from nausea and stress. Corpse Pose or Savasana: Lie down on your back on the floor. Rest your hands by your side and keep your eyes closed. Relax your body and mind. Release all your tensions and think about the life growing inside you. Stand up and cover your face with your hands. Take ten breaths and massage your face. It relaxes your whole body. Practice prenatal yoga to be at your healthiest during your pregnancy period. Read More : Follow These 5 Yoga Poses To Reduce Stubborn Belly Fat 9 Tips For Staying Fit And Healthy During Pregnancy What Are Popular Mind And Body Exercises Available At A Gym? Why Jumping On Trampolines Is More Beneficial Than Running Or Jogging? Bed Time Yoga To Sleep Well

Life with Braces: Tips from Surrey’s Orthodontic Experts

Surrey, British Columbia, is a dynamic city where nature's beauty intersects with a vibrant community and a growing healthcare landscape. Among its many offerings, Surrey is known for its exceptional orthodontic care, which is provided by experts committed to crafting beautiful smiles. Braces are an important part of strategies taken towards resolving a wide range of dental issues. For individuals suffering from crowded teeth or have concerns with rotated, gapped, or crooked teeth, it is a necessary solution to align the teeth. Furthermore, braces help improve the functionality of the teeth along with their appearance and health. Starting your journey with braces might seem daunting, but with guidance from skilled orthodontist surrey professionals, you can easily embark on this path. Whether for teens or adults, these expert tips will help you manage your orthodontic journey effectively. Getting to Know Braces Braces, a staple in orthodontic treatment, correct misalignment in teeth and jaws by applying steady pressure to shift teeth into desired positions. This path to a healthier smile demands patience, care, and a commitment to follow through with the necessary maintenance. If you are still a little confused with regards to the way braces actually help in resolving a wide range of orthodontic issues, then you should read the steps as discussed in the article. Mostly, people with gapped teeth, crooked teeth and crowded teeth might want to use braces. Simultaneously, if you are someone who has issues with the way their teeth fit together, which is also known as malocclusion, then using braces can help you get a better solution. With any concerns regarding braces, consulting orthodontists is the best way to go! Even though you can consult general dentists because some of them offer these services too. Pre-Braces Preparation There are different reasons why people get braces; therefore, individuals considering having braces should learn about how these work. It is also necessary to know about the different types of braces and how they work. Based on the types, you can decide on which one you will choose. At times, it is not on the patient but on the doctor to decide the type of braces that will be effective. It is also an important approach to understanding the severity of the condition and its necessary strategies to effectively bring change. For example, if you are using metal braces, it is visible when you smile. Or if you use tooth-colored ligatures, it will be less visible! Selecting an Orthodontist Your first step is finding the right orthodontist Surrey, a decision that can significantly impact your treatment experience. Surrey offers a wealth of skilled practitioners who prioritize personalized care and comfort, ensuring you find the best match for your needs. Establishing Clear Expectations Openly discuss your objectives and any apprehensions with your orthodontist. A clear understanding of your treatment's scope, duration, and anticipated results will help temper expectations and foster a smoother journey. The Braces Experience Apart from knowing the types of braces, it is important for you to understand that there will be some side effects, such as irritation on the inner cheeks, lips, or tongue. You might also have some jaw pain along with difficulty in eating! In the initial days after you get braces, you can get temporary discomfort. Especially when experiencing tightening, it is quite common to feel uncomfortable. Be aware before you use braces. Following the steps below, you will learn how to take care of your braces! 1. Prioritizing Dental Hygiene Maintaining excellent oral hygiene is more critical than ever with braces. Surrey's experts advise brushing after every meal and committing to daily flossing to avoid food build-up and potential dental complications. 2. Utilizing Orthodontic Wax Orthodontic wax can be a game-changer in mitigating irritation from braces to your mouth's inner linings. A bit of wax on troublesome brackets or wires can provide immediate comfort and protection. 3. Dietary Adjustments Certain foods, including hard, sticky, or chewy items, pose a risk to braces and should be avoided. To safeguard your braces, favour softer foods and consider cutting harder foods into smaller pieces. 4. Managing Discomfort Some discomfort is expected when braces are first fitted or adjusted. Surrey's orthodontists might recommend mild pain relievers, soft foods, or cold treats to ease gum soreness during these periods. 5. Consistent Follow-Ups Keeping up with orthodontic appointments is essential for timely adjustments and progress assessment. Regular visits are a key component of your treatment's success, ensuring any delays are minimized. Post-Braces Care A lot of people use colorful ligatures which are tiny elastic bands keeping the wires firmly in place. At times, individuals might use ceramic braces which work similar to metal braces however, they are less noticeable. It is due to the fact that the ligatures and wires along with the brackets of the braces are tooth colored thus, blending with your smile. If you are someone who is worried about the visuals of the braces, they can use these braces. I would like to bring to your attention that there is a high possibility that it will break. Ceramic braces are one of the most fragile braces which are unable to withstand pressure! So, try and take care of the retainers. 1. The Importance of Retainers Retainers are crucial post-braces for maintaining your teeth's new positions. Adhering to your orthodontist's guidance on retainer wear is imperative to prevent teeth from shifting back. 2. Embracing Your New Smile Completing your orthodontic treatment is an achievement worth celebrating. Not only does it enhance your appearance, but it also boosts oral health and confidence. 3. Ongoing Oral Health Maintaining oral health doesn't stop once braces are removed. Continue with regular dental hygiene practices and routine dental check-ups to keep your smile shining for years to come. Benefits Of Using Braces! Braces contribute effectively to your dental health because at times, if the teeth are misplaced, they might not be completely functional. Individuals might suffer significant problems such as pain, cavities, gum diseases, bad bites, injury, tooth decay and bone erosion. It is therefore important to consider the significance of using braces especially when they are used to correct malocclusion and bite problems. From a young age, you must have proper orthodontic care which not only takes care of the health of your teeth but also your overall oral health! If you are facing concerns such as overcrowding or bite problems, even though it is minor, you must address it. You should regularly clean your teeth along with evaluation of oral health on regular intervals. This will contribute to an overall understanding of the oral health consequences! Final Thoughts Embarking on an orthodontic journey in Surrey, BC, is a step towards attaining the smile you've always envisioned. By heeding local orthodontic specialists' advice, you can confidently navigate the experience, looking forward to the transformative results that await. Remember, the process is a partnership between you and your orthodontist to achieve lasting oral health and aesthetic benefits. Read Also: Rediscovering Your Smile: Cloverdale’s Dental Bridges How to Use Practice Analytics to Improve Your Dental Practice Emergency Dental Clinic Immediate Care When You Need It Most

Are Oncology Clinical Studies Facing Challenges?

How Can A Cardiologist Save Your Life?

Bolstering the God-Doctor-Patient Relationship: Expedites Healing

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Content Rally wrapped around an online publication where you can publish your own intellectuals. It is a publishing platform designed to make great stories by content creators. This is your era, your place to be online. So come forward share your views, thoughts and ideas via Content Rally.

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How Can A Cardiologist Save Your Life?

Bolstering the God-Doctor-Patient Relationship: Expedites Healing

Content Rally wrapped around an online publication where you can publish your own intellectuals. It is a publishing platform designed to make great stories by content creators. This is your era, your place to be online. So come forward share your views, thoughts and ideas via Content Rally.

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Follow Us

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