Are Oncology Clinical Studies Facing Challenges?

Published on: 31 August 2017 Last Updated on: 16 August 2019

Oncology clinical trials are a huge growth area and there is understandably a great deal of interest in treatments for cancer.

New treatment strategies such as immunotherapy and personalized medicine mean that clinical oncology has moved into an exciting stage. Demand for clinical studies is growing all the time, and clinical development is moving apace.

Interestingly, these developments mean that great progress is being made, but there have been some problems along the way. In August this year, reports emerged that the sheer number of oncology clinical trials means that pharmaceutical companies are having trouble finding enough patients to test new treatments on.

The issue has arisen due to the appetite for getting new cancer treatments to market, and the fact that these revolutionary treatment strategies are only effective in select patients. Drug companies want to get proprietary drugs to market so they can profit from their research, but testing them requires lots of patients.

Consider the fact that there are now more than 1,000 clinical studies of immunotherapy underway and it’s not hard to see why patient supply has become a problem. Fortunately, there are companies who can help researchers find the patients that they need.

One such company is INC Research, which boasts a team of experienced oncology specialists such as project managers, medical directors, CRAs and executive leadership. Over the past five years, INC Research has managed 310 studies at 7,278 sites involving 34,106 patients. If anyone can help researchers find the right patients, it’s an experienced company like INC Research.

Drug companies that have worked with INC Research report that there are real benefits, such as time- and cost-savings and real-time data gathering. The team has worked on incredibly complex trials involving investigational therapies like monoclonal antibodies, so they are ready for anything that you can throw at them.

Choosing the right clinical research organization (CRO) can make or break a study. INC Research offers a full spectrum service which handles data management and operational strategy, and the team also has a deep knowledge of the regulations related to Early Phase Oncology.

INC Research offers regulatory intelligence services to biotech companies across the globe, making sure that new treatments will get approved and make it to market. After all, improving available treatment options is the reason why companies choose to invest in cancer clinical trials.

From planning a trial to sourcing patients and collecting data, INC Research is a leader in its field. In an incredibly competitive environment, it is important to work with the best. With a long list of happy clients and glowing testimonials, drug companies can rest assured that their cancer clinical trial is in good hands with INC Research.

Read also:

Content Rally

Content Rally wrapped around an online publication where you can publish your own intellectuals. It is a publishing platform designed to make great stories by content creators. This is your era, your place to be online. So come forward share your views, thoughts and ideas via Content Rally.

View all posts

What You Can Do About Premature Ejaculation

Premature ejaculation, though a common condition in the male population, incites much concern and fear, especially if it transpires quite periodically. Instead of going through unverified channels to purchase cheap yet health-hazardous products, get priligy in the UK and follow these steps in dealing with PE. Premature ejaculation can also result from a lack of confidence arising out of the size and shape of your penis. It is exactly because of this reason that experts recommend that men who are conscious of their penis size should look at taking help from scientifically proven penis straighteners. If you want to know more about the products, please visit- https://jesextender.com/penis-straightener/. How To Deal With Premature Ejaculation: 1. How’s Are Your Stress Levels? Stress is often the cause of premature ejaculation in most. Yet it is the factor given the least attention. Mental stressors, as well as those similar to these, will prevent you from relaxing during coitus. It may sound ironic, that your blood vessels need to be relaxed in sexual intercourse. But biological observations show that the blood vessels connecting your bodily systems towards the reproductive system (i.e. CNS, cardiovascular system), along with the blood passageways in and around the penis, are greatly in control of erection and ejaculation. Of course, this is not to downplay the role of your central nervous system, where it all begins. We set this as number 1 on this list because it’s the variable that permits you the most control over, managing PE. Manage your stress. Commonly, stress has to do with heavy workloads and little rest or little sleep. Try to create a schedule (and working habits for efficiency) that will have you operating at your optimum without “overworking”, whilst leaving you with at least 7 hours of sleep every night. That is, amongst the rest of the leisurely activities in your day today (i.e. time with your family, etc.). You may immediately notice that after sticking to this new “balanced” schedule, PE, along with your prescribed PE medications, will appear less frequently. Plus, stress management is beneficial for your overall well-being, too. 2. Decreasing Sensitivity Of The Penis In Coitus: This isn’t the most conventional of the approaches towards moderating the occurrence of premature ejaculation. However, decreasing the sensitivity of the penis through the use of condoms has been proven effective for a number of patients. Penile sensitivity is not the root cause of premature ejaculation. But it is one of the minor factors. Note that the major root causes have to do with neurotransmitter blockage, blood, and blood vessel occlusion, and decreased capacity of the reproductive system (and its organs) to respond accordingly, from arousal to ejaculation. Then again, one of the most practical steps you may try to observe is wearing a condom. It isn’t fool-proof. Condoms are made so that they do not stand in the way of allowing sensory components to be activated around the penis, as close to when it does, when there isn’t a condom around it. In contrast, it still very lightly hampers sensation. A fraction, to say the least. While taking prescribed premature erection medication, it will be beneficial to be in the habit of wearing a condom during coitus, to aid the first. 3. Erectile Dysfunction Medication Is NOT Premature Ejaculation Medication: Though both treat male-targeted disorders, their functions are different from one another (as are ED against PE). If you also suffer from erectile dysfunction and have started undergoing treatment through ED medication, go to your telehealth physician and inquire about a prescription for PE as well. Your physician will then understand what treatment to prescribe, as ED medication may prompt the frequency of PE. The first has to do with causing an erection for a period as close to average as possible, enough for coitus. Hence, there’s some sort of delay in the process which may be what’s causing your PE. Be sure to get a diagnosis for both. Read Also: What You Need to Know When Having Gallstone Surgery 9 Ways Allergists Deal with their Own Allergies

Medicare Pros and Cons: Everything You Need to Know before Enrolling

Given that more than 40 million Americans benefit from what Medicare has to offer, there are many ways for older adults to stay healthy. Those with disabilities or who might be on the edge of the income limits should know the Medicare pros and cons before enrolling. There are plenty of reasons to choose Medicare or something else, so you need to know what suits your lifestyle. Here are some of the most common pros and cons that people bring up when they're struggling with this decision. Pro: Coverage for the Uncovered: One of the reasons that Medicare is such a powerful coverage tool is that it has offered coverage to millions of people who didn't have it. With this program, elder adults are covered and protected from medical catastrophes. With only half a million seniors uninsured from year to year now, it's made it so that almost no one over 65 has to live without protection. Because Medicare is for those who need it and have little means, it helps keep more Americans protected than ever. Without it, elderly Americans would be forced to pay for medical treatment they couldn't afford. Older people tend to need the most medical care, and so it's vital that they have affordable and manageable care. Since elderly Americans are often retired, they don't have the means to keep up with rising medical costs. People with disabilities get help under Medicare to pay for the challenging costs of care. Without this aid, they would be dependant on caretakers and stuck with few options for care. Con: There Are Massive Costs to Cover It: Put all the costs of Medicare together and you'll find that it costs nearly half a trillion dollars. While this might be a hard figure to quantify, it ends up being 15 percent of all of our federal spending. It's only going to continue to grow in the future. While there are several items in the federal budget that we don't question the cost of, this is one we have to consider in a realistic sense. The costs of medical care are constantly climbing ever higher and leading to insurmountable bills for the average American. Without any intervention by the federal government, the cost of healthcare and the cost of providing programs like Medicare will take a big cut out of taxes. Without Medicare, we would have a much bigger tax base. However, we would have people who are constantly sick and in need of care, clinics that are filled to the brim, and elderly people who had no way to care for themselves. While we could do some work to ensure that the money we have is spent more wisely, for now, we can imagine this money going to education or social justice. While it could help with programs to eliminate poverty, ultimately, more than half of bankruptcies are due to high medical bills. Pro: Get More with Medicare Advantage: For people who need more medical care than the average person, there are ways to supplement Medicare. Those people who find that they're at the limits of their Medicare coverage can sign up for the Medicare Advantage plan. Enrollment in this program is constantly growing and should be a powerful way for people to cover those massive increases in medical fees. Paying for private insurance is difficult if you're in the tax bracket eligible for Medicare. It's also redundant given that so much of what's covered by the standard medical plan is wrapped up in Original Medicare. However, with the help of Medicare Advantage, there is now a place for a third component that offers what many healthcare recipients need. The way this works is that insurance companies provide benefits related to what's missing from Medicare through a contract with the government. They offer them at competitive rates that are affordable to the average Medicare recipient. People taking advantage of these plans get everything they expect from Part A and Part B of Medicare but then get more dental and vision benefits. This extension provides some of what's missing in most of the other parts of this program. Con: Bad Health Is Expensive: If you're in poor health, you have an intimate view into just how expensive healthcare is. Even if you've got great insurance, you've seen the prices that come on the bill before you get your care deducted. You could be paying double or triple what a healthy person pays every year, even with healthcare. While you need to have great healthcare, you need to do what you can to stay healthy. Talk to your doctor about preventative care. You're never too old to take action to lower your healthcare costs and your need for supplemental care. There are many free preventative care programs that come standard with most Medicare plans. However, you need to take action to make sure you follow your doctors' recommendations and stay on top of your health. Many people who incur high bills with Medicare suffer from problems that preventative medicine could assist with. Even though this program costs very little from month to month, you need to manage your costs as they'll add up on a limited budget. If you're tight on money, Medicare supplements may be out of reach. This makes it all the more vital to staying on the good side of health. Medicare Pros and Cons Are Individual: Because everyone has their own healthcare needs and requirements, Medicare pros and cons vary from person to person. You need to get to know what you need and what you might need in the future before you decide on Medicare or any other insurance policy. As more people suffer more chronic health issues, check out our guide to watch the trend. Read Also: Finding The Right Hospital Complete Pregnancy Guide For Mumma’s To Be

10 Weird Facts About Antidepressants

People are working longer hours, have less time with family, and are constantly battling stressful situations. In addition, being constantly inundated with the news through social media can make anyone depressed. There's not enough time for daily yoga and meditation. As a result, many of us are turning to antidepressants to get us through these stressful times. But antidepressants come at a cost, and it's important to know all the facts. Some of these facts aren't common knowledge, and often your doctor won't even discuss them before prescribing antidepressants. Here are 10 weird facts about antidepressants that will surprise you. 1. We Don't Know How Antidepressants Work: Antidepressants have been around for a long time, and yet, we still don't know exactly how they work. And since everybody's depression is different, we don't know how well they work for varying degrees of depression or if they sufficiently treat depression at al. In fact, we don't even know if they're safe for long-term use. 13% of Americans take antidepressants, some for other illnesses like anxiety and fibromyalgia. Yet studies -- mostly paid for by pharmaceutical companies -- include only a few thousand people. Many of us have been told that depression is caused by a chemical imbalance in the brain, but we don't really know if that's true either. What most studies look at is our brain's level of serotonin. However, neither lowering nor increasing the level of serotonin in the brain reduces the symptoms of depression. If low levels of serotonin were the cause of depression, then antidepressants wouldn't take several weeks to work. They would work immediately, or at least within a few days, once the levels of serotonin increase. But they don't. Another interesting fact about antidepressants is that some don't even increase serotonin and still work as well as any other antidepressant. 2. All Antidepressants Are Equally Effective: It's a known fact about antidepressants that pharmaceutical companies spend a lot of money pushing one pill over another. Doctors aren't pharmacists and tend to push whatever antidepressants they're most familiar with. At times, they're buddies with the pharmaceutical sales rep. A fact about antidepressants is that there's no evidence that one antidepressant is more effective at treating depression than another. What a person needs to weigh is the cost and side effects, which can vary greatly from one person to another. There are over 30 different kinds of antidepressants available. They all work on different parts of the brain, inhibiting or increasing receptors of certain hormones. They have different side effects, and they all are equally effective. Sometimes they work, and sometimes they don't. 3. They Don't Work Immediately: All antidepressants take several weeks before they're fully effective. It can take anywhere from two weeks to a month before you know if it's the right antidepressant for you. One unfortunate fact about antidepressants is that many people have to cycle through several kinds of antidepressants, suffering from a variety of side effects before they find the right one. That's a long time for trial and error. And eventually, the effectiveness wears off over time. Many people build up a tolerance, and signs of depression return. Then you need to try a different antidepressant, and the trial and error process begins again. This could make anyone depressed. Fortunately, there are other treatments like TMS which don't require you to take any medication at all. 4. Dosage Makes No Difference Either: Many doctors start their patients off with a low dose and then gradually increase over time. There's no evidence that this is necessary or that higher dosages are more effective. Since this is the case, you're better off taking a low dose and having less negative side effects. It's a myth that a person will get better quicker if they are on a higher dosage of an antidepressant. 5. Antidepressants Can Help Your Sex Life: It is a pretty well-documented fact about antidepressants that one side effect is a lowered sex drive. That said, depression itself can lower your sex drive too. Interestingly, this low-libido side effect can have its benefits by helping men with premature ejaculation. Antidepressants can delay ejaculation, and for men who suffer from premature ejaculation, the delay can be a big help. One study found that men who took an SSRI a couple of hours before intercourse had longer ejaculation times compared to the placebo group. 6. Animals Get Depressed Too: Americans spend an estimated $15 million a year on medication for their depressed cats and dogs. Depression symptoms for animals aren't too different than those for people, so it's fairly easy to detect. However, it's difficult to treat animals with therapy. Instead, some veterinarians are treating pets with antidepressants. Zoo animals are on antidepressants too. They are being used to treat everything from aggression to obsessive-compulsive disorder. 7. You'll Feel Worse at First: Not only do antidepressants take a while to kick in, but your symptoms may be exacerbated. It's not uncommon for you to feel more tired, less hungry, less ambitious, and sadder. Things will get better. It just takes a while. In addition, the side effects don't help either. This is why doctors usually start a person off with a low dose, to reduce the intensity of side effects, before they find the right medication and dose. 8. Antidepressants Can Be Harmful: Antidepressants come with a long list of side effects, many of which mirror the symptoms of depression, lethargy, insomnia, nausea, anger, violence, and even suicidal thoughts. The side effects can sometimes be more debilitating than the illness it's treating. A person needs to seriously weigh the pros and cons. Often a person can mistake a side effect of the medication as a symptom of depression. Since we don't know how the drugs work, it's hard to know. Another fact about antidepressants is that once you start, it's not safe to quit cold turkey. A person should wean off of them slowly, and many aren't willing to do this. Quitting antidepressants quickly can be dangerous. 9. You Can Overdose on Antidepressants: Too much of a good thing can be too much. As mentioned, more isn't always better, but often people have prescribed higher doses of antidepressants anyway. You can overdose on antidepressants, and the symptoms of overdosing on them aren't always obvious. Zoloft overdose symptoms can include lethargy and nausea, which may be confused with ordinary side effects. Other, less obvious overdose symptoms include high blood pressure or inflammation of the pancreas, which can be mistaken for a cold or flu. However, if a person seems agitated, confused, or is vomiting, that's not normal. If someone taking antidepressants has these symptoms or becomes incoherent or unresponsive, call a doctor immediately A Zoloft overdose also can lead to a life-threatening condition called serotonin syndrome. Serotonin syndrome can occur when dangerously high levels of the neurotransmitter serotonin build up in the brain. 10. Antidepressants Can Interact with Other Drugs: It's very important to tell the doctor prescribing antidepressants if you're taking other drugs. It's also essential that you're honest about your use of recreational drugs and alcohol. All of these can have harmful interactions with antidepressants. Don't ever share your medication with anyone, especially if you don't know what other medications they might be taking or if they are using recreational drugs. Interactions can be deadly. Facts About Antidepressants Revealed Now that you know more about antidepressants, you can make a well-informed decision about taking them. Depression is debilitating, and some people battle with the disease their whole lives. For some, antidepressants are a last resort, and for others, they're hoping for a temporary solution that will give them an opportunity to have a better perspective. No matter the reason, there is no shame in being depressed or needing treatment. However, there are other methods of treating depression that can be used in conjunction with medication, such as therapy, exercise, diet, and natural remedies. Many of these have been proven to be equally effective. For more great articles about staying healthy, visit our blog. Read Also : 3 Ways To Connect With Nature And Quiet Your Mind Your Guide To HRT For Men All That You Need To Know About Dandy-Walker Syndrome

Are Oncology Clinical Studies Facing Challenges?

How Can A Cardiologist Save Your Life?

Bolstering the God-Doctor-Patient Relationship: Expedites Healing

Content Rally

Content Rally wrapped around an online publication where you can publish your own intellectuals. It is a publishing platform designed to make great stories by content creators. This is your era, your place to be online. So come forward share your views, thoughts and ideas via Content Rally.

Leave a Reply

Popular

Technologies For Creating A Startup Idea

How to Download Facebook Videos on Android?

7 Rules of Effective Ecommerce Web Design

The 10 WordPress Plugins Every Sucessful Blogger Uses

Follow Us

Recent

Agricultural Consulting Services: Boosting Farm Efficiency and Yield

5 Symptoms Women Entering Into Menopause Should Keep an Eye Out For

How to Download Airtel Thanks App and Recharge Seamlessly in 2025

How to Choose a Gift That Matches Their Personality Perfectly

Related

What You Can Do About Premature Ejaculation

Medicare Pros and Cons: Everything You Need to Know before Enrolling

10 Weird Facts About Antidepressants

Are Oncology Clinical Studies Facing Challenges?

Share this Article

How Can A Cardiologist Save Your Life?

Bolstering the God-Doctor-Patient Relationship: Expedites Healing

Content Rally wrapped around an online publication where you can publish your own intellectuals. It is a publishing platform designed to make great stories by content creators. This is your era, your place to be online. So come forward share your views, thoughts and ideas via Content Rally.

Leave a Reply

Popular

Follow Us

Recent

Related