As anabolic steroids are highly effective, yet when overused, they can be detrimental to health. The most critical of all is liver damage or toxicity. However, there are reports and instances that claim there are various dangerous side effects of the overuse of anabolic steroids that is rampant now. These are known as “doping” drugs used to enhance performance. Many bodybuilders and athletes use these drugs causing serious health problems. Precisely, anabolic steroids are testosterone offshoots used to increase muscle size and strength. Without a prescription, it is illegal to use steroids in the U.S. these are to be only used in certain cases with a doctor’s prescription. It stimulates muscle mass and bone strength useful from a health point of view. It is mainly prescribed in case of testosterone deficiency, delayed puberty, along disorders such as AIDS.
Exposure to such anabolic steroids for a longer time poses a threat to the liver and might advance as liver cancer. Regular consumption of such steroids can make you addicted and crave for it, affecting the liver adversely.
Besides, severe problems are witnessed in the body due to anabolic steroids and it mostly affects the liver causing complications. When enzymes named aminotransferases to leak out of liver cells in the bloodstream, it indicates liver damage. It may lead to liver damage condition known as cholestasis, which takes place because of anabolic steroids. It is a condition, in which digestive fluid bile, leaks out of the liver into the blood and causes symptoms like loss of appetite, itching, nausea, jaundice, and dark color urine, etcetera.
Do not take alkylated steroids:
Steroids like alkylated steroids harm life and have an adverse effect on liver function. These are oral steroids that are:
- Unable to remove toxins in the liver without letting them get in the blood
- Stop breakdown of toxins into the liver
- impedes the excretory liver function
Oral steroids (C17-Alpha Alkylated (C17-aa)) are responsible for the structural change in the hormone at the 17th carbon position. The purpose of such alteration is to enable the drugs to endure the first pass in the liver, where they can get into your system to benefit you. the bottom line is that C17-aa modification turns oral steroids toxic to the liver and it is unable to remove toxins. Hence, limit oral steroid use to 8 weeks considering the fact, the liver toxicity. However, the liver can rejuvenate, but this does not mean you can consume anything.
The side effects of oral steroids might increase the risk of hepatotoxic and might cause hepatic tumors, acute cholestatic syndrome, fatty liver disease, and chronic vascular injury. These changes can turn out to be fatal or recoverable.
The occurrence of chemical substitutions that take place in the testosterone in the body in two forms are:
- 17-alpha-alkylation, and
- 17-beta-esterification
Where metabolization of testosterone in the body takes place rapidly. The esterification of the 17-beta-hydroxyl group let molecules to be hydrophobic. On the other hand, 17-alpha- alkylation triggers inhibition with oxidation of metabolic deactivation of the 17-beta hydroxy group in the liver. Therefore, effectively administering the 17alpha-alkylated androgens orally. Mostly used anabolic oral steroids are stanozolol, methandienone, methandrostenolone, mesterolone, methenolone, oxandrolone, methyltestosterone. The oral forms do not cause instantaneous hepatotoxic and dilapidation.
Medical use of 17alpha-alkylated steroids for various purposes like muscle growth, weight gain in catabolic states, treating aplastic anemia, bone-marrow failure along with off-label doping purposes. These steroids were reported with the case of liver damage like nodular regeneration, cholestatic jaundice, hepatic adenoma, peliosis hepatis, and hepatocellular carcinoma.
Take non-alkylated steroids:
To be free from the liver adversities, using non-alkylated injectable steroid in the injectable forms undergoes the process of esterification 17-beta-hydroxy group making it soluble in lipids. This enables the slow release of steroids in circulation. Testosterone esters namely testosterone cypionate, enanthate, and decorate managed in oily suspension tend to release slowly in the aqueous plasma due to hydrophobicity. Extending its active duration. Whereas, a crucial metabolic path of testosterone and its artificial derivate is the oxidation of the 17-beta-hydroxy group forming 17-keto metabolites. Polar metabolites are inactive biologically in the body. The steroids that are injectable are stanozolol nandrolone decanoate, nandrolone undecanoate, testosterone enanthate, trenbolone acetate, trenbolone.
Using oral steroid alone is harmful as it put high pressure on the liver. So, to keep your liver healthy, use an attack of injectable steroids along with oral. It is great for cutting as well as bulking. Do not take more than 350-750mg per week of stack beyond six weeks of cycle duration.
Rely on supplements to protect the liver:
Be a smart steroid user and supplement your liver that restores and repair liver from any damages. N2Guardis highly popular among bodybuilders using oral steroids and do not in taking oral cycle without supplementing with it. Additionally, avoid alcohol consumption to avoid stress from the liver.
Aid offered by of N2Guard During And post Steroid Cycle:
- Regulates blood pressure
- Protects the liver from harm because of oral steroids
- It minimizes water retention
- Balances cholesterol levels
- Purifies the kidneys of steroid metabolites and excess protein feasting
- Purifies the blood from toxins and injurious metabolites
- Dissipates androgen receptors, make your next cycle more effective
- Maintains healthy, skeletal, reproductive, and digestive systems
By responsibly using the N2Guard, you can prevent your liver from any side effects of the steroid. N2Guard is used to enhance athletes throughout the world. It will keep you healthy during and beyond the cycle. It is the best support supplement and protects from any harm.
Benefits of using short steroid cycles:
Instead of long cycles, opt for short steroid cycles. As it keeps the liver activity in a normal condition without harming the liver. Exposure to high steroid use is dangerous. Besides, replace oral doses with injectable cycles to avoid severe health risks.
Take breaks during steroid cycling:
Regular use of steroids is not productive, instead, it can cause liver damage. More intake of steroids enables your body to resist it. Hence, making it inefficient after some time. Therefore, it is important to take breaks and enable your body to disengage from toxins. Let your body get back to normal function. Allow your liver to regenerate.
Liver function and ways to keeps it healthy:
The liver is a prime fat-burning organ. It also regulates the sex hormones testosterone. Therefore, the healthy liver function will enable the fat loss process smooth and easy. Keep your liver healthy by avoiding excess use of alcohol, do regular exercise, follow a healthy diet, avoid unnecessary medication. Ensure normal liver function before starting the steroid cycle. Avoid oral steroid cycle if facing liver issues.
- Cleanses blood
- Controls the amount of glucose supply
- Controls body cholesterol
- Regulate essential vitamins and minerals, such as iron and copper
- Oxidizes stored adipose tissue (fat) into energy by transporting it to mitochondria
- Produces vital body proteins indulged in transporting substances in the blood, providing resistance to infection, and clotting the blood
- Regulates sex hormones, thyroid hormones, adrenal hormones, and cortisone
- Produce bile salt, to immobilize fatty acids and eradicates toxic substances from the body
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